Reigning Copa del Rey champions FC Barcelona on Tuesday became the first side to book a place in the semifinals, edging second-division Albacete 2-1 away from home.

Lamine Yamal gave Barcelona the lead in the 39th minute, bending a left footed effort into the far corner after Marcus Rashford won the ball in midfield.

Fielding a reshuffled starting lineup, Barcelona initially found it difficult to penetrate a well organized Albacete defense before making the breakthrough. Rashford sent a low cross across the goalmouth in the third minute and squandered a clear opportunity five minutes later after being played in by Dani Olmo.

Albacete posed threats of their own in the opening half. Agus Medina struck straight at goalkeeper Joan Garcia, while Antonio Puertas twice forced saves from Garcia following turnovers in the Barcelona half.

Ronald Araujo extended Barcelona’s advantage in the 58th minute, heading home from a corner. Robert Lewandowski missed a chance to make it 3-0 soon afterward, shooting weakly at Raul Lizoain from a promising position.

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Lizoain later denied Ferran Torres after he replaced Lewandowski, as the match became more open. Albacete also missed chances, with Jefte Betancor heading over unmarked and later seeing a goal ruled out for offside in the 84th minute.

Javi Moreno pulled one back in the 87th minute with a diving header to set up a tense finish. Torres had a goal disallowed for offside, while Barcelona defender Gerard Martin cleared Fran Gamez’s chipped shot off the line to secure the win.

Two quarterfinals will be played Wednesday, with Alaves hosting Real Sociedad and Valencia facing Athletic Club. Real Betis meets Atletico Madrid on Thursday.