Russia launched a fresh wave of missile and drone attacks across Ukraine early Monday, killing at least 22 people and highlighting growing concerns over the country's air defence capabilities more than four years into Moscow's full-scale invasion.

The capital, Kyiv, bore the brunt of the assault, with at least 15 people killed and 56 others injured, according to city authorities. Ukraine's emergency service said another seven people were killed and 29 injured elsewhere in the Kyiv region.

Emergency crews continued search-and-rescue operations at the sites of damaged residential buildings, where ballistic missiles directly struck apartment blocks.

Ukrainian officials said all of the ballistic missiles launched by Russia reached their intended targets, underscoring the country's urgent need for additional US-made Patriot air defence interceptors.

President Volodymyr Zelenskyy is expected to raise the issue during this week's NATO summit in Ankara, Turkey, as Kyiv seeks greater military support from its allies.

Russia's Defence Ministry said the intensified attacks were in retaliation for recent long-range Ukrainian strikes inside Russian territory, which Moscow claims have disrupted fuel supplies and increased pressure on the Kremlin.

The latest barrage came just days after another Russian strike on Kyiv killed 31 people, marking the deadliest attack on the Ukrainian capital this year.

While Ukraine has gained momentum in recent months through expanded use of long-range drones targeting Russian supply routes and logistics, analysts say Moscow is increasingly exploiting weaknesses in Ukraine's air defence network.

Ukraine remains heavily dependent on Patriot missile systems to intercept Russian ballistic missiles, but supplies of the interceptors have come under pressure due to growing global demand, including from conflicts in the Middle East, raising concerns over Kyiv's ability to defend against future large-scale attacks.